CYP76AK1

Salvia miltiorrhiza CYP76A

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

11-hydroxyferruginol

PubChem ↗ CC(C)C1=C(C(=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C)O)O

CYP76AK1

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

11,20-dihydroxyferruginol

PubChem ↗ CC(C)C1=C(C(=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)CO)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP76AK1 from Salvia miltiorrhiza; only hydroxylation at C-20, no carboxylation.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:37542034 ↗
DOI: —
UniProt: A0A125QZE2 ↗
GenBank: —
NCBI TaxID: 226208 ↗

Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme