CYP76AK1

Salvia miltiorrhiza CYP76A

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

ferruginol

PubChem ↗ CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C)O

CYP76AK1

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

11-hydroxyferruginol

PubChem ↗ CC(C)C1=C(C(=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; 文献中提及SmCYP76AK1参与丹参酮生物合成，催化ferruginol羟基化；证据来自转基因毛状根中基因表达与代谢物变化。

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:36643739 ↗
DOI: 10.1093/hr/uhac238 ↗
UniProt: A0A125QZE2 ↗
GenBank: —
NCBI TaxID: 226208 ↗

The SmMYB36-SmERF6/SmERF115 module regulates the biosynthesis of tanshinones and phenolic acids in <i>salvia miltiorrhiza</i> hairy roots.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme