TkOSC1

Taraxacum koksaghyz

Asteraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

2,3-oxidosqualene

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C=C(\C)/CC/C=C(\C)/CCC1C(O1)(C)C)/C)/C)C

TkOSC1

ΔMass: +15.9949 Da fallback:~+16 Da (羟基化/氧化)

Product

β-amyrin

PubChem ↗ [H][C@]12[C@H](O)C=C3[C@]4([H])CC(C)(C)CC[C@]4(C)CC[C@@]3(C)[C@…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Heterologous expression in N. benthamiana and S. cerevisiae; product identified by GC-MS.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Terpenoids

Literature & public identifiers

PubMed: PMID:30976052 ↗
DOI: 10.1038/s41598-019-42381-w ↗
UniProt: MG646376 ↗
GenBank: MG646376 ↗
NCBI TaxID: 333970 ↗

The enzymes OSC1 and CYP716A263 produce a high variety of triterpenoids in the latex of Taraxacum koksaghyz.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme