TkOSC1

Taraxacum koksaghyz

Asteraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

2,3-oxidosqualene

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C=C(\C)/CC/C=C(\C)/CCC1C(O1)(C)C)/C)/C)C

TkOSC1

ΔMass: +0.0000 Da mismatch

Product

taraxasterol

PubChem ↗ C[C@H]1[C@@H]2[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Heterologous expression in Nicotiana benthamiana and Saccharomyces cerevisiae; product identified by GC-MS.

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:30976052 ↗
DOI: 10.1038/s41598-019-42381-w ↗
UniProt: MG646376 ↗
GenBank: MG646376 ↗
NCBI TaxID: 333970 ↗

The enzymes OSC1 and CYP716A263 produce a high variety of triterpenoids in the latex of Taraxacum koksaghyz.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme