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Quarantine ΔMass ✓ Hydroxylation

CYP82P3

Eschscholzia californica CYP82P

Papaveraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
dihydrosanguinarine
PubChem ↗ CN1CC2=C(C=CC3=C2OCO3)C4=C1C5=CC6=C(C=C5C=C4)OCO6
CYP82P3
ΔMass: +15.9949 Da hydroxylation(+15.9949)
Product
10-hydroxydihydrosanguinarine
PubChem ↗ CN1CC2=C(C3=C1C4=CC5=C(C=C4C=C3)OCO5)C(=CC6=C2OCO6)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Eschscholzia californica; catalyzes C-10 hydroxylation.

Reaction & quality gates

Mechanism
Hydroxylation (+15.99 Da)
Evidence type
In vitro
Confidence
High
Data tier
Quarantine
PDF audit quarantine (enzyme_miss_in_pdf;two_core_fields_in_text;review_structured_partial_core). pdf=41799975.pdf; enzyme_in_pdf=miss; issue=review_structured…
Substrate class
Alkaloids
Product class
Alkaloids

Literature & public identifiers

PubMed
PMID:41799975 ↗
DOI
10.3389/fpls.2026.1765290 ↗
UniProt
A0A2Z6BXV9 ↗
GenBank
NCBI TaxID
3467 ↗

Cytochrome P450 gene family: cross-pathway functional conservation, novel catalytic reactions, and synthetic biology-driven applications in plant secondary metabolism.