CYP76AH3

Salvia miltiorrhiza CYP76A

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

ferruginol

PubChem ↗ CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C)O

CYP76AH3

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

11-hydroxyferruginol

PubChem ↗ CC(C)C1=C(C(=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Based on reference [13] cited in the text; SmCYP76AH3 hydroxylates ferruginol to 11-hydroxyferruginol in tanshinone pathway.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
PDF audit quarantine (enzyme_miss_in_pdf;weak_text_core;review_text_weak_core). pdf=40391389.pdf; enzyme_in_pdf=miss; issue=review_text_weak_core; core=weak_te…
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:40391389 ↗
DOI: 10.1093/hr/uhaf096 ↗
UniProt: A0A0Y0GRS3 ↗
GenBank: —
NCBI TaxID: 226208 ↗

The SmWRKY32-SmbHLH65/SmbHLH85 regulatory module mediates tanshinone biosynthesis in <i>Salvia miltiorrhiza</i>.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme