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Quarantine ΔMass ✓ Oxidation

CYP716A83

Centella asiatica CYP716A

Apiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
b-amyrin
PubChem ↗ C[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C…
CYP716A83
ΔMass: +29.9742 Da methyl_to_carboxyl(+29.9742)
Product
oleanolic acid
PubChem ↗ C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CaCYP716A83 catalyzes a-amyrin/b-amyrin to ursolic acid/oleanolic acid based on sequence identity and correlation analysis.

Reaction & quality gates

Mechanism
Oxidation
Evidence type
In vivo
Confidence
High
Data tier
Quarantine
PDF audit quarantine (enzyme_miss_in_pdf;two_core_fields_in_text;review_structured_partial_core). pdf=38283979.pdf; enzyme_in_pdf=miss; issue=review_structured…
Substrate class
Terpenoids
Product class
Organic acids

Literature & public identifiers

PubMed
PMID:38283979 ↗
DOI
10.3389/fpls.2023.1295186 ↗
UniProt
A0A1I9Q5Y4 ↗
GenBank
NCBI TaxID
48106 ↗

Integrated metabolome and transcriptome analysis identifies candidate genes involved in triterpenoid saponin biosynthesis in leaves of <i>Centella asiatica</i> (L.) Urban.