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Quarantine ΔMass ✓ Oxidation

KO

Stevia rebaudiana

Asteraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
ent-kaurene
PubChem ↗ C[C@@]12CCCC([C@H]1CC[C@]34[C@H]2CC[C@H](C3)C(=C)C4)(C)C
KO
ΔMass: +29.9742 Da methyl_to_carboxyl(+29.9742)
Product
ent-kaurenoic acid
PubChem ↗ C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@H](C3)C(=C)C4)(C)C(=O…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; 本文鉴定KO（ent-kaurene oxidase，CYP701A3）催化ent-kaurene生成ent-kaurenoic acid，为SGs/GAs共同中间体。证据来自转录组注释和通路描述。

Reaction & quality gates

Mechanism
Oxidation
Evidence type
In vivo
Confidence
High
Data tier
Quarantine
PDF audit quarantine (enzyme_miss_in_pdf;two_core_fields_in_text;review_structured_partial_core). pdf=28928460.pdf; enzyme_in_pdf=miss; issue=review_structured…
Substrate class
Terpenoids
Product class
Organic acids

Literature & public identifiers

PubMed
PMID:28928460 ↗
DOI
10.1038/s41598-017-12025-y ↗
UniProt
Q0Q2G8 ↗
GenBank
—
NCBI TaxID
55670 ↗

Molecular dissection of transcriptional reprogramming of steviol glycosides synthesis in leaf tissue during developmental phase transitions in Stevia rebaudiana Bert.