CYP85

Solanum lycopersicum

Solanaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

6-deoxocastasterone

PubChem ↗ C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C…

CYP85

ΔMass: +13.9793 Da mismatch

Product

castasterone

PubChem ↗ C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=O)[C@@H]4[C@@]3…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Functional expression in yeast confirmed C-6 oxidation of 6-deoxoCS to CS; also detected 6a-hydroxycastasterone as intermediate.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=mismatch
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:9990098 ↗
DOI: 10.1073/pnas.96.4.1761 ↗
UniProt: Q43147 ↗
GenBank: —
NCBI TaxID: 4081 ↗

The tomato DWARF enzyme catalyses C-6 oxidation in brassinosteroid biosynthesis.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme