CYP714E88

Ilex asprella

Aquifoliaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

oleanolic acid

PubChem ↗ C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C…

CYP714E88

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

hederagenin

PubChem ↗ C[C@]12CC[C@@H]([C@@]([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; IaAO4 catalyzes C-23 hydroxylation of oleanolic acid to hederagenin, confirmed by authentic standard.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Organic acids
Product class: Other

Literature & public identifiers

PubMed: PMID:35422828 ↗
DOI: 10.3389/fpls.2022.831401 ↗
UniProt: —
GenBank: —
NCBI TaxID: 185493 ↗

Cytochrome P450 Monooxygenase/Cytochrome P450 Reductase Bi-Enzymatic System Isolated From <i>Ilex asprella</i> for Regio-Specific Oxidation of Pentacyclic Triterpenoids.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme