CYP90B50

Repeated evolution CYP90B

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

cholesterol

PubChem ↗ C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3…

CYP90B50

ΔMass: +31.9898 Da mismatch

Product

16S,22S-dihydroxycholesterol

PubChem ↗ C[C@@H]([C@H]1[C@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; In vitro yeast microsome assay; also in vivo in N. benthamiana and yeast.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=mismatch
Substrate class: Steroids
Product class: Steroids

Literature & public identifiers

PubMed: PMID:31324795 ↗
DOI: 10.1038/s41467-019-11286-7 ↗
UniProt: XP_015619622 ↗
GenBank: XP_015619622 ↗
NCBI TaxID: —

Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme