CYP82X1

Papaver somniferum CYP82X

Papaveraceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

1-hydroxy-13-O-acetyl-N-methylcanadine

PubChem ↗ CC(=O)O[C@@H]1[C@H]2C3=C(C4=C(C=C3CC[N+]2(CC5=C1C=CC(=C5OC)OC)C…

CYP82X1

ΔMass: +14.9876 Da mismatch

Product

4'-O-desmethyl-3-O-acetylpapaveroxine

PubChem ↗ CC(=O)O[C@H]([C@H]1C2=C(C3=C(C=C2CCN1C)OCO3)O)C4=C(C(=C(C=C4)OC…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt Other; Other; Ring-opening reaction; reconstituted in yeast; structure confirmed by NMR.

Reaction & quality gates

Mechanism: Other
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=mismatch
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:27378283 ↗
DOI: 10.1038/ncomms12137 ↗
UniProt: I3V6B7 ↗
GenBank: —
NCBI TaxID: 3469 ↗

Engineering biosynthesis of the anticancer alkaloid noscapine in yeast.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme