← Back to reactions
Silver mismatch Hydroxylation

CYP94B3

Arabidopsis thaliana CYP94B

Brassicaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
jasmonoyl-L-isoleucine
PubChem ↗ CC/C=C\C[C@H]1C(=O)CC[C@@H]1CC(=O)N[C@H](C(=O)O)[C@@H](C)CC
CYP94B3
ΔMass: +0.0000 Da mismatch
Product
12-hydroxy-jasmonoyl-L-isoleucine
PubChem ↗ CC/C=C\C[C@H]1C(=O)CC[C@@H]1CC(=O)N[C@H](C(=O)O)[C@@H](C)CC

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP94B3 loss-of-function mutant showed reduced 12OH-JA-Ile; overexpression increased 12OH-JA-Ile and 12COOH-JA-Ile.

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
In vivo
Confidence
High
Data tier
Silver
mass=mismatch
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:25210037 ↗
DOI
10.1074/jbc.m114.603084 ↗
UniProt
Q9SMP5 ↗
GenBank
CS302217 ↗
NCBI TaxID
3702 ↗

Endoplasmic reticulum-associated inactivation of the hormone jasmonoyl-L-isoleucine by multiple members of the cytochrome P450 94 family in Arabidopsis.