CYP76M8

Oryza sativa CYP76M

Poaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

syn-pimaradiene

PubChem ↗ C[C@]1(CCC2C(=CCC3[C@@]2(CCCC3(C)C)C)C1)C=C

CYP76M8

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

6β-hydroxy-syn-pimaradiene

PubChem ↗ C[C@]1(CC[C@@H]2C(=C[C@H]([C@@H]3[C@@]2(CCCC3(C)C)C)O)C1)C=C

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; PMID 22215681, recombinant expression in E. coli, in vitro assay with microsomes, GC-MS and NMR characterization.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:22215681 ↗
DOI: 10.1074/jbc.m111.305599 ↗
UniProt: Q6YTF1 ↗
GenBank: —
NCBI TaxID: 4530 ↗

Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme