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Silver mismatch Hydroxylation

CYP75B81

Citrus clementina

Rutaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
naringenin
PubChem ↗ C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
CYP75B81
ΔMass: +0.0000 Da mismatch
Product
3'-hydroxylated naringenin
PubChem ↗ C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Yeast assay with recombinant CitF3'H; highest relative activity toward naringenin.

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=mismatch
Substrate class
Phenylpropanoids
Product class
Phenylpropanoids

Literature & public identifiers

PubMed
PMID:36818367 ↗
DOI
10.1093/hr/uhac283 ↗
UniProt
GenBank
NCBI TaxID
85681 ↗

Genome-wide analysis of cytochrome P450 genes in <i>Citrus clementina</i> and characterization of a CYP gene encoding flavonoid 3'-hydroxylase.