AsAKS2

Alstonia scholaris

Apocynaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

rhazimol

PubChem ↗ C/C=C\1/CN2CC[C@@]34C5=CC=CC=C5N=C3[C@@H]2C[C@@H]1[C@@]4(CO)C(=…

AsAKS2

ΔMass: +42.0106 Da mismatch

Product

akuammiline

PubChem ↗ C/C=C\1/CN2CC[C@@]34C5=CC=CC=C5N=C3[C@@H]2C[C@H]1C4(COC(=O)C)C(…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt Other; Other; BAHD acetyltransferase; acetyl-CoA dependent.

Reaction & quality gates

Mechanism: Other
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:36349266 ↗
DOI: 10.1039/d2sc03612f ↗
UniProt: A0A9E7LUL3 ↗
GenBank: —
NCBI TaxID: 52822 ↗

Deciphering and reprogramming the cyclization regioselectivity in bifurcation of indole alkaloid biosynthesis.