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Gold ΔMass ✓ Hydroxylation

CYP80B3

Expression data CYP80B

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
(S)-N-methylcoclaurine
PubChem ↗ CN1CCC2=CC(=C(C=C2[C@@H]1CC3=CC=C(C=C3)O)O)OC
CYP80B3
ΔMass: +15.9949 Da hydroxylation(+15.9949)
Product
3'-hydroxy-N-methylcoclaurine
PubChem ↗ CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)O)O)O)OC

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Expression data from leaf transcriptomes of Berberis species; no direct in vitro enzyme assay reported.

Reaction & quality gates

Mechanism
Hydroxylation (+15.99 Da)
Evidence type
In vivo
Confidence
Medium
Data tier
Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:36297700 ↗
DOI
10.3390/plants11202676 ↗
UniProt
Q9SP06 ↗
GenBank
NCBI TaxID

Comparative Transcriptomics for Genes Related to Berberine and Berbamine Biosynthesis in Berberidaceae.