GlOSC1

Gynostemma longipes

Cucurbitaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

2,3-oxidosqualene

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C=C(\C)/CC/C=C(\C)/CCC1C(O1)(C)C)/C)/C)C

GlOSC1

ΔMass: +18.0106 Da mismatch

Product

dammarenediol-II

PubChem ↗ CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1CC[C@H]3[C@]2(CC[C@@H]4[C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; GlOSC1 is a dammarenediol-II synthase (DDS) identified in Gynostemma longipes. The reaction was confirmed by yeast expression assay and LC-MS analysis (PMID: 35401630).

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:35401630 ↗
DOI: 10.3389/fpls.2022.852377 ↗
UniProt: —
GenBank: —
NCBI TaxID: 555431 ↗

Integrated Metabolomic and Transcriptomic Analysis and Identification of Dammarenediol-II Synthase Involved in Saponin Biosynthesis in <i>Gynostemma longipes</i>.