MT2

Solanum lycopersicum

Solanaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

3-HAA

PubChem ↗ C1=CC(=C(C(=C1)O)N)C(=O)O

MT2

ΔMass: +14.0157 Da mismatch

Product

3-HAA methyl ester

PubChem ↗ COC(=O)c1cccc(O)c1N

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt Other; Other; SlMT2 methylates 3-hydroxyanthranilic acid (3-HAA) to form 3-HAA methyl ester (1) in yeast. Confirmed by feeding assays and LC-MS/MS.

Reaction & quality gates

Mechanism: Other
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:33127687 ↗
DOI: 10.1126/sciadv.abd1143 ↗
UniProt: A0AB70BME4 ↗
GenBank: —
NCBI TaxID: 4081 ↗

Discovery of a previously unknown biosynthetic capacity of naringenin chalcone synthase by heterologous expression of a tomato gene cluster in yeast.