TgTPS1

Tectona grandis

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

geranylgeranyl diphosphate

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)/C)C

TgTPS1

ΔMass: -177.9432 Da mismatch

Product

miltiradiene

PubChem ↗ CC(C)C1=CCC2=C(C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Transient expression in Nicotiana benthamiana; forms miltiradiene.

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Terpenoids

Literature & public identifiers

PubMed: PMID:30698701 ↗
DOI: 10.1093/gigascience/giz005 ↗
UniProt: —
GenBank: —
NCBI TaxID: 41396 ↗

A chromosomal-scale genome assembly of Tectona grandis reveals the importance of tandem gene duplication and enables discovery of genes in natural product biosynthetic pathways.