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Silver mismatch Hydroxylation

CYP706V7

Expressed in CYP706V

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
ent-kaurenoic acid
PubChem ↗ C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@H](C3)C(=C)C4)(C)C(=O…
CYP706V7
ΔMass: +434.2880 Da mismatch
Product
15β-hydroxy-ent-kaurenoic acid
PubChem ↗ C[C@@H]1CC(C)(C)C2CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H]([C@@H](C)CC[…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Expressed in A. oryzae; product isolated and characterized by NMR spectroscopy.

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
In vivo
Confidence
High
Data tier
Silver
mass=mismatch
Substrate class
Organic acids
Product class
Organic acids

Literature & public identifiers

PubMed
PMID:42054221 ↗
DOI
10.1021/jacs.6c06067 ↗
UniProt
GenBank
NCBI TaxID

Chemoenzymatic Synthesis with Plant Oxidases and Metabolic Engineering Enable Rapid Access to Rare Gibberellins.