CYP72A565

Camptotheca acuminata CYP72A

Nyssaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

loganin

PubChem ↗ C[C@H]1[C@H](C[C@H]2[C@@H]1[C@@H](OC=C2C(=O)OC)O[C@H]3[C@@H]([C…

CYP72A565

ΔMass: -2.0157 Da ketone_formation(-2.0157)

Product

secologanin

PubChem ↗ COC(=O)C1=CO[C@H]([C@@H]([C@@H]1CC=O)C=C)O[C@H]2[C@@H]([C@H]([C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Camptotheca acuminata; cleavage of C7-C8 bond.

Reaction & quality gates

Mechanism: Ketone formation (-2.02 Da)
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
PDF audit quarantine (enzyme_miss_in_pdf;two_core_fields_in_text;review_structured_partial_core). pdf=41799975.pdf; enzyme_in_pdf=miss; issue=review_structured…
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:41799975 ↗
DOI: 10.3389/fpls.2026.1765290 ↗
UniProt: A0A4Y5UJ61 ↗
GenBank: —
NCBI TaxID: 16922 ↗

Cytochrome P450 gene family: cross-pathway functional conservation, novel catalytic reactions, and synthetic biology-driven applications in plant secondary metabolism.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme