CYP80Q1

Biosynthesis of CYP80Q

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

(S)-N-methylcoclaurine

PubChem ↗ CN1CCC2=CC(=C(C=C2[C@@H]1CC3=CC=C(C=C3)O)O)OC

CYP80Q1

ΔMass: -2.0157 Da fallback:~-2 Da (成酮/脱氢)

Product

proaporphines

PubChem ↗ CN1CCC2=CC(=C(C3=C2C1CC34C=CC(=O)C=C4)O)OC

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; PMID=41776991, 正文第4页: 'NnCYP80Q1 and AcCYP80Q8' 催化C1′–C8 coupling生成proaporphines。产物为泛指，但原文明确。

Reaction & quality gates

Mechanism: Ketone formation (-2.02 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:41776991 ↗
DOI: 10.1016/j.xplc.2026.101786 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Biosynthesis of benzylisoquinoline alkaloids and its evolution in plants.