CYP72A68V2

Medicago sativa CYP72A

Fabaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

oleanolic acid

PubChem ↗ C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C…

CYP72A68V2

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

hederagenin

PubChem ↗ C[C@]12CC[C@@H]([C@@]([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; MtCYP72A68v2 from Medicago sativa catalyzes C-23 hydroxylation of oleanolic acid to hederagenin in S. cerevisiae (strain WA10).

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
PDF audit quarantine (enzyme_miss_in_pdf;two_core_fields_in_text;review_structured_partial_core). pdf=40951686.pdf; enzyme_in_pdf=miss; issue=review_structured…
Substrate class: Organic acids
Product class: Other

Literature & public identifiers

PubMed: PMID:40951686 ↗
DOI: 10.1016/j.synbio.2025.08.007 ↗
UniProt: H1A985 ↗
GenBank: —
NCBI TaxID: 3879 ↗

De novo biosynthesis of Asperosaponin VI in <i>Saccharomyces cerevisiae</i>.