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Quarantine ΔMass ✓ Hydroxylation

CYP90G11

Ornithogalum saundersiae CYP90G

Asparagaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
22(R)-hydroxycholesterol
PubChem ↗ C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H…
CYP90G11
ΔMass: +15.9949 Da hydroxylation(+15.9949)
Product
16b,22R-dihydroxycholesterol
PubChem ↗ O[C@@H]1[C@H]([C@@H]([C@@H](CCC(C)C)O)C)[C@]2(CC[C@@H]3[C@]4(CC…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; In vitro activity with WAT11 microsomes co-expressing OsCYP90G11 and OsCPR2.

Reaction & quality gates

Mechanism
Hydroxylation (+15.99 Da)
Evidence type
In vitro
Confidence
High
Data tier
Quarantine
PDF audit quarantine (enzyme_miss_in_pdf;weak_text_core;review_text_weak_core). pdf=40545634.pdf; enzyme_in_pdf=miss; issue=review_text_weak_core; core=weak_te…
Substrate class
Steroids
Product class
Steroids

Literature & public identifiers

PubMed
PMID:40545634 ↗
DOI
10.1111/pbi.70080 ↗
UniProt
GenBank
NCBI TaxID
484171 ↗

The clarification of two hydroxylation steps in the conversion of cholesterol to OSW-1 in Ornithogalum saundersiae.