AgCPS5

Aconitum gymnandrum

Ranunculaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

geranylgeranyl pyrophosphate

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)/C)C

AgCPS5

ΔMass: -177.9432 Da mismatch

Product

ent-8,13-copalyl diphosphate

PubChem ↗ C[C@@]12CCCC([C@H]1CC[C@]34[C@H]2C[C@H](CC3)C(=C)C4)(C)C

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Recombinant protein expressed in E. coli; product identified by GC-MS comparison with PcTPS1.

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:36362268 ↗
DOI: 10.3390/ijms232113463 ↗
UniProt: ON881909 ↗
GenBank: ON881909 ↗
NCBI TaxID: 215071 ↗

Integrating Metabolomics and Transcriptomics to Unveil Atisine Biosynthesis in <i>Aconitum gymnandrum</i> Maxim.