AgCPS2

Aconitum gymnandrum

Ranunculaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

geranylgeranyl pyrophosphate

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)/C)C

AgCPS2

ΔMass: +0.0000 Da mismatch

Product

ent-copalyl diphosphate

PubChem ↗ C/C(=C\COP(=O)(O)OP(=O)(O)O)/CC[C@@H]1C(=C)CC[C@H]2[C@]1(CCCC2(…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Recombinant protein expressed in E. coli; product identified by GC-MS comparison with ZmCPS2.

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:36362268 ↗
DOI: 10.3390/ijms232113463 ↗
UniProt: ON881907 ↗
GenBank: ON881907 ↗
NCBI TaxID: 215071 ↗

Integrating Metabolomics and Transcriptomics to Unveil Atisine Biosynthesis in <i>Aconitum gymnandrum</i> Maxim.