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Quarantine no_smiles Glycosylation

LpUGT95

Lysionotus pauciflorus

Gesneriaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
nevadensin
PubChem ↗ COC1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)O)OC)O
LpUGT95
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
nevadensin 5-O-glucoside
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Recombinant LpUGT95 in E. coli with UDP-glucose produced minor nevadensin 5-O-glucoside (peak II) confirmed by MS/MS; weaker activity than 7-O-glucosylation.

Reaction & quality gates

Mechanism
Glycosylation
Evidence type
In vitro
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Glycosides

Literature & public identifiers

PubMed
PMID:36123741 ↗
DOI
10.1186/s12934-022-01921-2 ↗
UniProt
OP096439 ↗
GenBank
OP096439 ↗
NCBI TaxID
48809 ↗

Integrated multi-omics analysis and microbial recombinant protein system reveal hydroxylation and glycosylation involving nevadensin biosynthesis in Lysionotus pauciflorus.